after a dosage increase. if you are older. if you have an existing lung problem. The side effects of codeine are similar to those of other opioids, and include: constipation. headache or dizziness. fatigue or drowsiness (especially soon after a dose) loss of appetite, nausea and vomiting. Always take medicines exactly as prescribed your doctor. a liquid that you swallow – this contains 25mg of codeine in a 5ml spoonful. The usual dose of codeine is 15mg to 60mg. adults – one or two 30mg tablets, taken every 4 hours, up to a maximum of 8 tablets (240mg) in 24 hours. children (aged 12 to 17 years) – one or two 30mg tablets (or one or two 5ml spoonfuls of liquid), taken every 6 hours.Jul 14, 2021 · Like other opioids, codeine can be toxic in large amounts. Symptoms of an opioid overdose include: bluish fingernails and lips. confusion. breathing problems, such as slow and labored breathing ... Codeine is used to relieve mild to moderately severe pain, and it belongs to the drug class of opioid analgesics. Codeine has also been prescribed to prevent coughing, though the antitussive administration is most often in liquid formulations and in conjunction with other medications. ( 1, 2) The hepatic CYP2D6 enzyme metabolizes a quarter of ...Feb 13, 2023 · Codeine is a medication used in the management and treatment of chronic pain. It is in the opioid class of medications. This activity outlines the indications, action, and contraindications for codeine as a valuable agent in treating chronic pain and off-label use in cough, persistent diarrhea, and restless leg syndrome. In addition, this activity will highlight the mechanism of action ... Jun 23, 2020 · Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent. Common side effects include ... Adults and children 12 years of age and older—5 milliliters (mL) (1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children 6 to 11 years of age—2.5 to 5 mL (0.5 to 1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children younger than 6 years of age—Use is not recommended. Missed DoseMar 24, 2023 · If you are 65 or older, use promethazine and codeine with care. You could have more side effects. The chance of very bad side effects may be higher in children. This may be more likely to happen in children who have breathing problems. Deadly breathing problems have happened with the use of codeine in some children. 5.1 Addiction, Abuse, and Misuse. Promethazine with Codeine Oral Solution contains codeine, a Schedule V controlled substance. As an opioid, Promethazine with Codeine Oral Solution exposes users to the risks of addiction, abuse, and misuse [see DRUG ABUSE AND DEPENDENCE (9)], which can lead to overdose and death [seeOVERDOSAGE (10)].Jan 10, 2021 · Pharmacological properties of promethazine. Promethazine is a phenothiazine derivative and a histamine (H1) receptor antagonist that is commonly used for symptomatic relief of nausea and vomiting, for allergic conditions, motion sickness and common cold, and for short-term use treatment of insomnia in adults or as a paediatric sedative (). Jan 29, 2020 · Lean is a very sweet drink that blends soda with cough syrup containing codeine. Some formulas also add candy or sweetening syrup. Users may also mix in promethazine, which is an antihistamine ... NHS medicines information on codeine – what it's used for, side effects, dosage and who can take it.codeine/promethazine systemic. Drug class: upper respiratory combinations. Codeine/promethazine systemic is used in the treatment of: Cough; codeine/pseudoephedrine systemic. Brand names: Cycofed, Nucodine, Codar D, Nucofed, EndaCof-DC Drug class: upper respiratory combinations. Codeine/pseudoephedrine systemic is used in the treatment of: of codeine due to a CYP2D6 polymorphism. Promethazine HCl and Codeine Phosphate Oral Solution is contraindicated in children younger than 12 years of age and in children younger than 18 years of age following tonsillectomy and/or adenoidectomy (see CONTRAINDICATIONS). Avoid the use of Promethazine HCl and Codeine PhosphateNHS medicines information on codeine – what it's used for, side effects, dosage and who can take it.Phenergan is also found in combination with other medications such as phenylephrine (Prometh Hydrochloride), codeine (Prometh VC), or dextromethorphan (Promethazine DM) What is Phenergan? Phenergan belongs to a group of drugs called phenothiazines. It works by changing the actions of chemicals in your brain. Promethazine also acts as an ...Lean is a very sweet drink that blends soda with cough syrup containing codeine. Some formulas also add candy or sweetening syrup. Users may also mix in promethazine, which is an antihistamine ...Codeine Information. Codeine is an opioid pain reliever used to treat mild to moderately severe pain. It is also used, usually in combination with other medications, to reduce coughing. Codeine is ...Dec 13, 2022 · severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out. Side effects such as confusion and severe drowsiness may be more likely in older adults. Common promethazine side effects may include: drowsiness, dizziness; ringing in your ears; Oxycodone (OxyContin, Roxicodone, Oxaydo, Xtampza ER) and codeine are both narcotic pain relievers. Both are also used as cough suppressants similar to morphine and hydrocodone. Both are potentially addictive and cause withdrawal symptoms. Similar side effects of oxycodone and codeine include lightheadedness, dizziness, sedation, nausea, vomiting, constipation, dry mouth, itching, and rash.5.1 Addiction, Abuse, and Misuse. Promethazine with Codeine Oral Solution contains codeine, a Schedule V controlled substance. As an opioid, Promethazine with Codeine Oral Solution exposes users to the risks of addiction, abuse, and misuse [see DRUG ABUSE AND DEPENDENCE (9)], which can lead to overdose and death [seeOVERDOSAGE (10)].Codeine is a prescription opioid, which is used as a pain reliever, and promethazine is an antihistamine. Both drugs have sedative effects and can produce feelings of drowsiness, mild euphoria and ...Hycofenix, Rezira (hydrocodone, pseudoephedrine, guaifenesin) Tussionex, Pennkinetic, Vituz (hydrocodone, chlorpheniramine, pseudoephedrine) Generic combinations of hydrocodone and homatropine. Giving prescription cough medicines to kids or teens is dangerous. They can slow their breathing to dangerous levels and can even be fatal.Oct 10, 2022 · Initial dose: 15 to 60 mg orally up to every 4 hours as needed. Maximum dose: 360 mg in 24 hours. Comments: Initial doses should be individualized taking into account severity of pain, response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse. Doses higher than 60 mg have not been shown to improve pain ... What is Codeine Phosphate-Promethazine HCl? Codeine Phosphate-Promethazine HCl is a combination medicine used to treat cold or allergy symptoms such as runny nose, sneezing, and cough. Codeine Phosphate-Promethazine HCl contains an opioid (narcotic) cough medicine, and may be habit-forming. Codeine Phosphate-Promethazine HCl may also be used ...Promethazine with codeine syrup is indicated for the temporary relief of coughs and upper respiratory tract symptoms related to allergies or the common cold. What is promethazine used for? Promethazine is an antihistamine, similar to products available over-the-counter like Benadryl, Claritin, Zyrtec, and Allegra. Antihistamines are typically ...Combining opioids and promethazine can cause too much drowsiness. And it could also slow your breathing to a dangerous level. If you need to take them together, your healthcare provider may lower the dosage of your pain medication. You may be surprised that promethazine is available in combination with codeine (an opioid).NHS medicines information on codeine – what it's used for, side effects, dosage and who can take it.Codeine is a drug in some prescription pain medicines. It is in the class of drugs known as opioids, which refers to any synthetic, semisynthetic, or natural drug that has morphine-like properties. Codeine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.NHS medicines information on codeine – what it's used for, side effects, dosage and who can take it. The codeine in Promethazine VC with Codeine can cause newborns to experience withdrawal syndrome, which is life-threatening for infants. Withdrawal syndrome is a condition that develops when Promethazine VC with Codeine crosses through the placenta and causes the unborn baby to become dependent on the medication.Promethazine Prescription only Codeine is an effective pain reliever; however, it is addictive, may cause constipation, and its pain-relieving effects vary markedly between individuals. Codeine should only be used for pain relief... more Prescription only Promethazine may be used to relieve allergy symptoms and nausea.Aug 15, 2018 · 5.1 Addiction, Abuse, and Misuse. Promethazine with Codeine Oral Solution contains codeine, a Schedule V controlled substance. As an opioid, Promethazine with Codeine Oral Solution exposes users to the risks of addiction, abuse, and misuse [see DRUG ABUSE AND DEPENDENCE (9)], which can lead to overdose and death [seeOVERDOSAGE (10)]. Codeine is also used to treat diarrhoea. It works in the central nervous system and the brain to block pain signals to the rest of the body. It also reduces the anxiety and stress caused by pain. Codeine is available on prescription and comes as tablets, a liquid you swallow and as an injection. Codeine injections are usually only given in ...A total of 486 drugs are known to interact with codeine / guaifenesin : 122 major drug interactions (477 brand and generic names) 361 moderate drug interactions (1496 brand and generic names) 3 minor drug interactions (7 brand and generic names) A total of 748 drugs are known to interact with codeine / promethazine : 181 major drug interactions ...cough. darkened urine. darkening of the skin. diarrhea. difficult or trouble breathing. difficulty swallowing. dizziness. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position. fainting.Aug 1, 2023 · Promethazine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. It can sometimes close up the bronchial tubes (air passages of the lungs) and make breathing difficult. Codeine belongs to the group of medicine ... Promethazine with Codeine Oral Solution is a combination of codeine, an opioid agonist; and promethazine, a phenothiazine, indicated for the temporary relief of cough and upper respiratory symptoms associated with allergy or the common cold in patients 18 years of age and older.Oct 26, 2021 · The codeine in Promethazine VC with Codeine can cause newborns to experience withdrawal syndrome, which is life-threatening for infants. Withdrawal syndrome is a condition that develops when Promethazine VC with Codeine crosses through the placenta and causes the unborn baby to become dependent on the medication. Dec 12, 2022 · For all patients taking this drug: This drug has an opioid drug in it. Opioid drugs can put you at risk for addiction, abuse, and misuse. Misuse or abuse of this drug can lead to overdose and death. If you have questions, talk with your doctor. This drug may cause very bad and sometimes deadly breathing problems. Like other opioids, codeine can be toxic in large amounts. Symptoms of an opioid overdose include: bluish fingernails and lips. confusion. breathing problems, such as slow and labored breathing ...Initial dose: 15 to 60 mg orally up to every 4 hours as needed. Maximum dose: 360 mg in 24 hours. Comments: Initial doses should be individualized taking into account severity of pain, response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse. Doses higher than 60 mg have not been shown to improve pain ...Codeine is a drug in some prescription pain medicines. It is in the class of drugs known as opioids, which refers to any synthetic, semisynthetic, or natural drug that has morphine-like properties. Codeine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.The most frequently reported codeine-containing medicines in the cases were acetaminophen with codeine used for pain, and promethazine with codeine (with or without phenylephrine) used for cough ... Aug 29, 2023 · Codeine cough suppressants like promethazine/codeine should only be an option for short-term use — and only in adults. This type of cough syrup is available by prescription. However, it is a controlled substance and habit-forming. Best cough medicine for kids Acetaminophen/codeine oral solution. Each 5 mL of acetaminophen/codeine solution contains 12 mg of codeine and 120 mg of acetaminophen. The typical dose is 15 mL by mouth every 4 hours as needed. Do not take more than 3,000 mg to 4,000 mg of acetaminophen within a 24-hour period.Codeine is also available in conjunction with the anti-nausea medication promethazine in the form of a syrup. Brand named as Phenergan with Codeine or in generic form as promethazine with codeine, it began to be mixed with soft drinks in the 1990s as a recreational drug, called 'syrup', 'lean', or ' purple drank '. [61]Find patient medical information for promethazine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. ... (such as codeine, hydrocodone), ...Codeine is a drug in some prescription pain medicines. It is in the class of drugs known as opioids, which refers to any synthetic, semisynthetic, or natural drug that has morphine-like properties. Codeine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. Promethazine is a phenothiazine medication that blocks the signals in your brain and body causing you to experience cold and allergy symptoms like a runny nose and sneezing. Codeine is an opioid medication that works in your brain to lessen your urge to cough. What is Promethazine / codeine used for?Lean, also known as purple drank, purp, sizzurp, syrup, wock or oil, and several other names, is a recreational drug beverage, prepared by mixing prescription strength cough or cold syrup containing codeine and promethazine with a soft drink. The beverage originated in Houston and is popular in hip hop culture, especially within the Southern ... codeine/promethazine systemic. Drug class: upper respiratory combinations. Codeine/promethazine systemic is used in the treatment of: Cough; codeine/pseudoephedrine systemic. Brand names: Cycofed, Nucodine, Codar D, Nucofed, EndaCof-DC Drug class: upper respiratory combinations. Codeine/pseudoephedrine systemic is used in the treatment of: Apr 26, 2023 · codeine. Used for Pain. Codeine is an opioid pain medication that's taken by mouth and used to treat mild-to-moderate pain. Common side effects of codeine include constipation, itching, sleepiness, and dizziness. It's typically not a first-choice pain medication because it can lead to more serious harm, such as slowed breathing and addiction. NHS medicines information on codeine – what it's used for, side effects, dosage and who can take it.Uses for Phenergan w/Codeine. Promethazine and codeine combination is used to relieve cough, runny or stuffy nose, sneezing, or other symptoms caused by allergies or the common cold. Promethazine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body.The codeine in Promethazine VC with Codeine can cause newborns to experience withdrawal syndrome, which is life-threatening for infants. Withdrawal syndrome is a condition that develops when Promethazine VC with Codeine crosses through the placenta and causes the unborn baby to become dependent on the medication.Promethazine and codeine combination is used to relieve cough, runny or stuffy nose, sneezing, or other symptoms caused by allergies or the common cold. Promethazine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body.See full list on drugs.com Each 5 mL (one teaspoonful), for oral administration contains: Promethazine hydrochloride 6.25 mg; codeine phosphate 10 mg. Alcohol 7%. Inactive Ingredients: Ascorbic acid, citric acid, FD&C ... Codeine: Narcotic analgesics, including codeine, exert their primary effects on the central nervous system and gastrointestinal tract. The analgesic ...Promethazine is an antihistamine that relieves watery eyes, itchy eyes /nose/throat, runny nose, and sneezing. Codeine is an opioid cough suppressant ( antitussive) that affects a certain part... Codeine is a prescription opioid, which is used as a pain reliever, and promethazine is an antihistamine. Both drugs have sedative effects and can produce feelings of drowsiness, mild euphoria and ...Adults and children 12 years of age and older—5 milliliters (mL) (1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children 6 to 11 years of age—2.5 to 5 mL (0.5 to 1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children younger than 6 years of age—Use is not recommended. Missed DoseCombining opioids and promethazine can cause too much drowsiness. And it could also slow your breathing to a dangerous level. If you need to take them together, your healthcare provider may lower the dosage of your pain medication. You may be surprised that promethazine is available in combination with codeine (an opioid).Generic name: codeine / promethazine systemic Drug class: upper respiratory combinations. For consumers: dosage, interactions, side effects. For professionals: Prescribing Information. Expand current row for information about Hycodan Hycodan: 8.5Codeine Information. Codeine is an opioid pain reliever used to treat mild to moderately severe pain. It is also used, usually in combination with other medications, to reduce coughing. Codeine is ...Jan 29, 2020 · Lean is a very sweet drink that blends soda with cough syrup containing codeine. Some formulas also add candy or sweetening syrup. Users may also mix in promethazine, which is an antihistamine ... Phenergan with Codeine (promethazine and codeine) is a combination of an antihistamine, sedative, anti-nausea drug, cough suppressant, pain reliever, and cough suppressant used to treat common cold symptoms and cough. Common side effects of Phenergan with Codeine include dizziness, restlessness, inability to sleep, palpitations, and changes in muscle tone and more. Withdrawal symptoms may ...Sep 14, 2018 · Codeine is a prescription opioid, which is used as a pain reliever, and promethazine is an antihistamine. Both drugs have sedative effects and can produce feelings of drowsiness, mild euphoria and ... Codeine is a narcotic pain reliever (analgesic) used to treat mild to moderately severe pain frequently combined with Tylenol or aspirin. Common side effects include itching, rash, stomach pain, constipation, shortness of breath, nausea, lightheadedness, and dizziness. Codeine is a controlled narcotic and it has the potential for abuse. Dependence and addiction can occur with codeine, even at ...PROMETHAZINE; CODEINE (proe METH a zeen; KOE deen) treats the symptoms of the common cold, allergies, or flu. It works by reducing cough, a runny or stuffy nose, and red, itchy eyes. It is a combination of an antihistamine and an opioid cough suppressant. This medicine may be used for other purposes; ask your health care provider or pharmacist ...Sep 14, 2022 · Promethazine Dosage and Administration Administration. Administer orally, rectally, or by deep IM injection. Also administered by IV injection. However, FDA states that deep IM injection is the preferred method for administration of promethazine hydrochloride injection because of risks associated with IV administration (see Warnings Regarding Parenteral Administration under Boxed Warning). Feb 4, 2021 · Codeine (3-methylmorphine) is an alkaloid prepared from the methylation of morphine derived from poppy seeds ( Papaver somniferum) [ 1 ]. It is used to manage mild to moderate pain, including chronic cancer pain, and has antitussive, antistress, and antidiarrheal properties [ 2, 3, 4 ]. In the body, a small amount of codeine is metabolized to ... Aug 1, 2023 · Descriptions. Promethazine and codeine combination is used to relieve cough, runny or stuffy nose, sneezing, or other symptoms caused by allergies or the common cold. Promethazine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny ... Constipation. Itching. Slowed breathing. Changes in vision. Over long periods of time, codeine abuse can cause an increase in lung infections, bowel damage, sleep disorders, irregular heart rate, and even brain damage. Beyond the physical effects, drug addiction tends to have a profound impact on life satisfaction.Aug 15, 2018 · 5.1 Addiction, Abuse, and Misuse. Promethazine with Codeine Oral Solution contains codeine, a Schedule V controlled substance. As an opioid, Promethazine with Codeine Oral Solution exposes users to the risks of addiction, abuse, and misuse [see DRUG ABUSE AND DEPENDENCE (9)], which can lead to overdose and death [seeOVERDOSAGE (10)]. Find patient medical information for promethazine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. ... (such as codeine, hydrocodone), ...Promethazine HCl and Codeine Phosphate Oral Solution in adolescents 12 to 18 years of age who have other risk factors that may increase their sensitivity to the respiratory depressant effects of codeine. Promethazine and Respiratory Depression in Children Postmarketing cases of respiratory depression, including fatalities have been reported with Each 5 mL (one teaspoonful), for oral administration contains: Promethazine hydrochloride 6.25 mg; codeine phosphate 10 mg. Alcohol 7%. Inactive Ingredients: Ascorbic acid, citric acid, FD&C ... Codeine: Narcotic analgesics, including codeine, exert their primary effects on the central nervous system and gastrointestinal tract. The analgesic ...
Promethazine HCl and Codeine Phosphate Oral Solution in adolescents 12 to 18 years of age who have other risk factors that may increase their sensitivity to the respiratory depressant effects of codeine. Promethazine and Respiratory Depression in Children Postmarketing cases of respiratory depression, including fatalities have been reported with . Lowepercent27s bathroom faucets brushed nickel
codeine/promethazine systemic. Drug class: upper respiratory combinations. Codeine/promethazine systemic is used in the treatment of: Cough; codeine/pseudoephedrine systemic. Brand names: Cycofed, Nucodine, Codar D, Nucofed, EndaCof-DC Drug class: upper respiratory combinations. Codeine/pseudoephedrine systemic is used in the treatment of: Promethazine Prescription only Codeine is an effective pain reliever; however, it is addictive, may cause constipation, and its pain-relieving effects vary markedly between individuals. Codeine should only be used for pain relief... more Prescription only Promethazine may be used to relieve allergy symptoms and nausea.Promethazine with Codeine Oral Solution is a combination of codeine, an opioid agonist; and promethazine, a phenothiazine, indicated for the temporary relief of cough and upper respiratory symptoms associated with allergy or the common cold in patients 18 years of age and older.Pediatric. Use of Promethazine VC with codeine oral liquid in children and Promethazine, phenylephrine, and codeine oral solution in children younger than 12 years of age is not recommended. It should not be used to relieve pain after surgery to remove tonsils or adenoids in any children. Severe breathing problems and deaths have been reported ...Feb 6, 2023 · Phenergan is also found in combination with other medications such as phenylephrine (Prometh Hydrochloride), codeine (Prometh VC), or dextromethorphan (Promethazine DM) What is Phenergan? Phenergan belongs to a group of drugs called phenothiazines. It works by changing the actions of chemicals in your brain. Promethazine also acts as an ... Descriptions. Acetaminophen and codeine combination is used to relieve mild to moderate pain. Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including serious liver damage.Aug 1, 2023 · cough. darkened urine. darkening of the skin. diarrhea. difficult or trouble breathing. difficulty swallowing. dizziness. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position. fainting. Avoid sunlamps and tanning beds. This medicine may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist.Avoid sunlamps and tanning beds. This medicine may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist.Pediatric. Use of Promethazine VC with codeine oral liquid in children and Promethazine, phenylephrine, and codeine oral solution in children younger than 12 years of age is not recommended. It should not be used to relieve pain after surgery to remove tonsils or adenoids in any children. Severe breathing problems and deaths have been reported ...Promethazine Codeine is a combination medicine used to treat allergy symptoms such as runny nose, sneezing, and cough. Promethazine with Codeine contains an opioid (narcotic) cough medicine, and may be habit-forming. Promethazine with Codeine may also be used for purposes not listed in this medication guide. Promethazine with Codeine side effectscodeine/promethazine systemic. Drug class: upper respiratory combinations. Codeine/promethazine systemic is used in the treatment of: Cough; codeine/pseudoephedrine systemic. Brand names: Cycofed, Nucodine, Codar D, Nucofed, EndaCof-DC Drug class: upper respiratory combinations. Codeine/pseudoephedrine systemic is used in the treatment of: Jan 29, 2020 · Lean is a very sweet drink that blends soda with cough syrup containing codeine. Some formulas also add candy or sweetening syrup. Users may also mix in promethazine, which is an antihistamine ... of codeine due to a CYP2D6 polymorphism. Promethazine HCl and Codeine Phosphate Oral Solution is contraindicated in children younger than 12 years of age and in children younger than 18 years of age following tonsillectomy and/or adenoidectomy (see CONTRAINDICATIONS). Avoid the use of Promethazine HCl and Codeine PhosphateMay 22, 2023 · Independently, Codeine and Promethazine are both depressants that largely affect the nervous system, and when they’re combined, the result is intense and euphoric sedation. In larger quantities, lean has been found to induce hallucinations and lucid dreams or nightmares; some artists have claimed it to assist in their creative process. Oct 9, 2012 · -Codeine (an opiate that treats pain and coughs) -Hydrocodone (an opiate used to treat moderate to severe pain) -Phenacetin (an analgesic that's not used much anymore) When codeine is used to reduce coughing, it works by decreasing the activity in the part of the brain that causes coughing. Codeine is also available in combination with acetaminophen (Capital and Codeine, Tylenol with Codeine), aspirin, carisoprodol, and promethazine and as an ingredient in many cough and cold medications.Phenergan with Codeine (promethazine and codeine) is a combination of an antihistamine, sedative, anti-nausea drug, cough suppressant, pain reliever, and cough suppressant used to treat common cold symptoms and cough. Common side effects of Phenergan with Codeine include dizziness, restlessness, inability to sleep, palpitations, and changes in muscle tone and more. Withdrawal symptoms may ....